Veterinarian Rack Hansen is drawn into a sinister mystery when he uncovers the cause behind the bizarre deaths of local livestock. His investigation reveals that a massive migration of tarantulas is threatening his town. As the spiders begin to invade, chaos ensues, and a handful of residents find themselves barricaded in a secluded hotel, desperate for survival. With time running out, Rack must devise a plan to combat the deadly swarm before it consumes the entire community. Tension rises as the battle against these relentless arachnids escalates.