Iliza Shlesinger takes the helm of this innovative late-night talk show, exploring various themes through thought-provoking questions. Each episode invites audience participation and features engaging field segments, all seasoned with Iliza's signature humor. As she navigates both serious sociopolitical matters and lighter, more trivial topics, she seeks to uncover answers while keeping the atmosphere lively and entertaining. With her sharp wit and relatable commentary, Iliza crafts conversations that resonate with viewers, making each week a fresh dive into the complexities of contemporary life.