Ladies Up showcases the comedic talents of Prashasti Singh, Kaneez Surka, Supriya Joshi, and Niveditha Prakasam, who are making waves in the Indian comedy scene. Each episode features these rising stars delivering their unique brand of unfiltered humor, tackling various topics with wit and charm. Their performances highlight the diverse experiences of women in comedy, offering both laughter and insight. With a vibrant mix of perspectives, the series invites audiences to enjoy a refreshing take on stand-up that resonates with contemporary themes and relatable life moments.